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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
28.79
Human Site:
Y1439
Identified Species:
48.72
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
Y1439
K
E
S
S
A
K
L
Y
I
N
H
T
P
P
P
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
Y1441
K
E
S
S
A
K
L
Y
I
N
H
T
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
Y1439
K
E
S
S
A
K
L
Y
I
N
H
T
P
P
P
Dog
Lupus familis
XP_538164
1593
182721
Y1439
K
E
S
S
A
K
L
Y
I
N
H
T
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
Y1439
K
D
S
S
A
K
L
Y
I
N
H
N
P
P
P
Rat
Rattus norvegicus
XP_233081
1594
182711
Y1439
K
D
S
S
A
K
L
Y
I
N
H
N
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
Y1494
K
E
P
S
A
K
H
Y
I
N
H
T
T
P
I
Chicken
Gallus gallus
XP_420332
1593
182430
Y1440
K
D
S
S
T
K
H
Y
I
N
H
T
T
P
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
G1355
L
E
K
N
A
G
A
G
S
L
K
S
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
R1483
H
Y
E
E
F
E
G
R
M
R
D
L
S
S
V
Honey Bee
Apis mellifera
XP_393587
1354
156054
R1205
E
I
T
N
G
D
T
R
I
E
K
E
S
K
D
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
D1284
S
D
E
P
S
K
K
D
E
K
E
S
P
K
D
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
E1414
G
E
R
V
R
K
V
E
K
K
S
S
H
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
Q1499
N
K
T
V
T
D
D
Q
S
T
H
R
D
Q
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
73.3
66.6
N.A.
20
N.A.
0
6.6
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
73.3
N.A.
33.3
N.A.
13.3
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
58
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
0
0
0
15
8
8
0
0
8
0
8
0
29
% D
% Glu:
8
50
15
8
0
8
0
8
8
8
8
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
8
8
8
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
15
0
0
0
65
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
65
0
0
0
0
0
8
% I
% Lys:
58
8
8
0
0
72
8
0
8
15
15
0
0
15
0
% K
% Leu:
8
0
0
0
0
0
43
0
0
8
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
15
0
0
0
0
0
58
0
15
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
0
0
50
58
50
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
8
0
0
15
0
8
0
8
0
8
0
% R
% Ser:
8
0
50
58
8
0
0
0
15
0
8
22
15
8
0
% S
% Thr:
0
0
15
0
15
0
8
0
0
8
0
43
15
0
8
% T
% Val:
0
0
0
15
0
0
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _